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Updated: Oct 9, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
Solitary renal cell carcinoma metastasis to the hand: the need for wide excision or amputation
M A Ghert1, J M Harrelson, S P Scully
1Division of Orthopaedic Surgery, Box 3312, Duke University Medical Center, Durham, NC 27710, USA.
Abstract:
Metastatic renal cell carcinoma responds poorly to chemotherapy or radiation therapy and is associated with a dismal survival rate. In cases of a solitary acrometastasis, the literature supports complete resection of the lesion in an effort to prolong survival. We report a patient who presented with a solitary metachronous renal cell metastasis to the middle phalanx of the index finger. The lesion was correctly identified as a renal cell metastasis and aggressive surgical management was performed with curative intent.