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[Acute generalized exanthematous pustulosis in hypercalcemia].
G Perceau1, C Derancourt, V Salmon-Ehr
1Service de Dermatologie, CHU Reims.
Annales De Dermatologie Et De Venereologie
|February 15, 2001
Summary
A severe rash resembling drug reactions was caused by acute parvovirus B19 infection. This case highlights rare viral triggers for generalized exanthematous pustulosis.
Area of Science:
- Dermatology
- Virology
- Infectious Diseases
Background:
- Generalized exanthematous pustulosis (GEP) is typically associated with drug hypersensitivity.
- Viral infections are rare causes of GEP.
Observation:
- A 23-year-old male presented with severe fever, rash, and systemic symptoms including hypovolemic shock.
- The patient had no history of drug intake.
- Laboratory findings included hyperleukocytosis and evidence of acute parvovirus B19 infection.
Findings:
- Diagnosis of acute parvovirus B19 infection confirmed by virology tests.
- The patient's physician also showed evidence of acute parvovirus B19 infection.
- Clinical and biological presentation mimicked drug hypersensitivity syndrome.
Implications:
- This case underscores parvovirus B19 as a potential viral etiology for GEP.
- Recognizing viral causes is crucial for accurate diagnosis and management of GEP.
- Further research into rare viral triggers for GEP is warranted.