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Differences in the two-dimensionally measured laser Doppler flow at different skin localisations
M Stücker1, J Steinberg, U Memmel
1Department of Dermatology, Ruhr University, Bochum, Germany. M.Stuecker@derma.de
Skin Pharmacology and Applied Skin Physiology
|February 15, 2001
Summary
This study quantified skin perfusion across 20 areas using laser Doppler perfusion imaging (LDPI). Facial skin exhibited higher perfusion than the trunk and extremities, with lips showing the highest values.
Area of Science:
- Dermatology
- Microcirculation Research
- Medical Imaging
Background:
- Cutaneous microcirculation exhibits significant heterogeneity.
- High-resolution two-dimensional laser Doppler perfusion imaging (LDPI) enables reproducible spatial and temporal perfusion measurements.
Purpose of the Study:
- To quantify skin perfusion in 20 defined areas using LDPI in healthy volunteers.
- To investigate potential differences in skin perfusion related to age and gender.
Main Methods:
- Utilized two-dimensional laser Doppler perfusion imaging (LDPI).
- Measured skin perfusion in 60 healthy young and old volunteers across 20 distinct skin areas.
Main Results:
- Facial skin perfusion was significantly higher than trunk and extremities.
- Lips (1.47 AU) showed the highest perfusion, followed by chin, nose, forehead, and cheek.
- Extremities and trunk showed moderate perfusion (0.40-0.49 AU), with the lowest on the soles (0.31 AU).
- Men tended to have higher perfusion than women; no significant age-related differences were found.
Conclusions:
- Regional perfusion differences are crucial for evaluating pathological skin.
- Moderate age and gender variations can be tolerated when comparing investigation groups.