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Pancreatic involvement by non-Hodgkin's lymphoma
1Department of Surgery, Yamanashi Red Cross Hospital, Yamanashi, Japan; Second Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Journal of Hepato-Biliary-Pancreatic Surgery
|February 17, 2001
Summary
This case report details a rare instance of non-Hodgkin's lymphoma affecting the pancreas. Early diagnosis and chemotherapy are crucial for managing this aggressive pancreatic lymphoma.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Non-Hodgkin's lymphoma (NHL) can rarely manifest as a pancreatic mass.
- Pancreatic lymphomas often present with non-specific symptoms, complicating diagnosis.
Observation:
- A 63-year-old male presented with a large pancreatic head tumor causing anemia and ileus due to invasion of adjacent organs.
- Initial diagnosis was uncertain, necessitating surgical resection (pancreatoduodenectomy and right hemicolectomy).
Findings:
- Histopathology and immunohistochemistry confirmed diffuse mixed-type, B-cell phenotype non-Hodgkin's lymphoma.
- The patient developed severe congestive heart failure post-surgery and did not receive chemotherapy.
Implications:
- Highlights the importance of considering lymphoma in pancreatic masses, even without obstructive jaundice.
- Emphasizes the need for definitive diagnosis, surgical intervention, and prompt chemotherapy for improved outcomes in pancreatic lymphoma.