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Updated: Aug 13, 2026

Rapid Analysis of Chromosome Aberrations in Mouse B Lymphocytes by PNA-FISH
Published on: August 19, 2014
Quantitative estimation of chromosome aberration frequency in cancer patients induced by endogenous and exogenous
A N Chebotarev1, O P Kirichenko, O I Sokolova
1Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, Russia.
Abstract:
In patients with skin melanoma and colon cancer, cell distribution by the number of chromosome aberrations cannot be described by Poisson distribution, but corresponds to a bipopulation model combining the Poisson and geometric distributions. In contrast to the control, in patients with malignant tumors, cells with geometric distribution possess the majority of chromosomal aberrations.
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