Related Experiment Video
Updated: Jul 24, 2026

09:24
Decellularization and Recellularization of Whole Livers
Published on: February 5, 2011
Functional activity of hepatocytes in tissue fragments in a new bioreactor biological artificial liver
V V Solov'ev1, V S Akatov, E I Lezhnev
1Laboratory of Cytotechnology, Institute of Theoretical and ExperimentalBiophysics, Russian Academy of Sciences, Pushchino. soloval@mail.ru
Bulletin of Experimental Biology and Medicine
|February 24, 2001
Abstract:
Functional activity of hepatocytes in a new bioreactor designed for culturing of liver tissue fragments under perfusion conditions was tested. Specific hepatic functions such as ammonium detoxification, urea and protein synthesis, and P-450-dependent metabolism of p-nitroanisole were maintained for 1.5 days. The bioreactor can be used as a bioartificial liver support apparatus.

