Influence of tuberculin on ventilatory parameters in patients with chronic bronchitis

The influence of tuberculin administered in aerosol on the ventilatory parameters in patients suffering from chronic bronchitis has been studied. The diameter of the tuberculin skin reaction 1 day after inhalation of tuberculin was found to be related to a decrease in maximal 1-sec forced expiratory volume and maximal midexpiratory flow-rate. Significant decrease in the parameters of dynamic pulmonary ventilation occurred only in a certain proportion (24.6%) of tuberculin-positive patients suffering from chronic bronchitis of the obstructive type.