Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Why skin cancer?].

R Gniadecki1, H C Wulf

  • 1H:S Bispebjerg Hospital, dermatologisk afdeling D.

Ugeskrift for Laeger
|February 24, 2001
PubMed
Summary
This summary is machine-generated.

This review covers common skin cancers like basal cell carcinoma and squamous cell carcinoma, detailing their molecular causes and the role of UV radiation in skin cancer development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consequences of changing illumination procedures in photodynamic therapy.

Photodiagnosis and photodynamic therapy·2026
Same author

Editorial: Pioneers & pathfinders: 10 years of frontiers in medicine.

Frontiers in medicine·2025
Same author

An international Delphi consensus to define a clinically appropriate definition of disease modification for plaque psoriasis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

Cyclic photodynamic therapy delays first onset of actinic keratoses in renal transplant recipients: a 5-year randomized controlled trial with 12-month follow-up.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Psoriasis and metabolic syndrome: implications for the management and treatment of psoriasis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Intertriginous mycosis fungoides with T follicular helper cell phenotype progressing to Sézary syndrome.

Clinical and experimental dermatology·2021
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Area of Science:

  • Dermatology
  • Oncology
  • Molecular Biology

Context:

  • Basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma are the most common skin cancers.
  • Advances in skin cancer research enable identification of environmental factors and molecular pathology in cutaneous carcinogenesis.

Purpose:

  • To review the current understanding of ultraviolet radiation's carcinogenic role in skin cancer.
  • To summarize other potential etiological factors in skin cancer development.

Summary:

  • Alterations in the sonic hedgehog signaling pathway drive basal cell carcinoma development.
  • p53 protein deactivation is crucial in squamous cell carcinoma pathogenesis.
  • The pathogenesis of malignant melanoma requires further elucidation.

Related Experiment Videos

Impact:

  • Provides insights into the molecular mechanisms of common skin cancers.
  • Highlights the significance of environmental factors, particularly UV radiation, in skin carcinogenesis.
  • Establishes a foundation for further research into melanoma pathogenesis and other contributing factors.