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[Mercilon - the optimal oral contraceptive]
E Rachev1, L Damianov, G Kolarov
1State University Hospital Maichin Dom.
Akusherstvo I Ginekologiia
|February 24, 2001
Summary
Mercilon, an oral contraceptive, demonstrated excellent contraceptive efficacy with a Pearl Index of 0.00. It also provided good menstrual cycle control and a favorable safety profile with minimal adverse effects in women.
Area of Science:
- Reproductive Health
- Pharmacology
- Clinical Trials
Background:
- Oral contraceptives are widely used for family planning.
- Assessing the safety and efficacy of specific oral contraceptive formulations is crucial.
Purpose of the Study:
- To evaluate the contraceptive efficacy of Mercilon.
- To assess the impact of Mercilon on the menstrual cycle.
- To determine the safety profile, including effects on lipid profile and organ function.
Main Methods:
- A survey involving 32 women using Mercilon.
- Monitoring of contraceptive efficacy using the Pearl Index.
- Assessment of menstrual cycle patterns.
- Evaluation of lipid profiles, liver function, kidney function, and coagulation parameters.
- Documentation of adverse effects.
Main Results:
- Achieved excellent contraceptive effect with a Pearl Index of 0.00.
- Demonstrated good control over the menstrual cycle.
- No adverse effects on lipid profile, liver, kidney, or coagulation system function were observed.
- Minor side effects reported in only 5% of participants.
Conclusions:
- Mercilon exhibits high contraceptive efficacy.
- Mercilon offers good menstrual cycle regulation.
- Mercilon presents a favorable safety profile with minimal adverse events.