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Related Experiment Videos

Decrease in tear secretion and corneal sensitivity after laser in situ keratomileusis.

J M Benitez-del-Castillo1, T del Rio, T Iradier

  • 1Instituto de Investigaciones Oftalmologicas Ramon Castroviejo, Facultad de Medicina, Universidad Complutense, Madrid, Spain.

Cornea
|February 24, 2001
PubMed
Summary

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Laser in situ keratomileusis (LASIK) temporarily reduces tear secretion and corneal sensitivity in myopia correction. These functions may not fully recover for up to nine months post-surgery.

Area of Science:

  • Ophthalmology
  • Refractive Surgery

Background:

  • Myopia affects a significant portion of the population.
  • Laser in situ keratomileusis (LASIK) is a common surgical procedure for myopia correction.

Purpose of the Study:

  • To evaluate the impact of LASIK on tear secretion and corneal sensitivity.
  • To assess the recovery timeline for these functions post-LASIK.

Main Methods:

  • A prospective study involving 48 eyes (24 patients) undergoing LASIK for myopia.
  • Tear secretion (tear function index) and corneal sensitivity (Cochet-Bonnet esthesiometer) were measured preoperatively and at multiple time points up to 9 months post-surgery.

Main Results:

  • Tear secretion and corneal sensitivity were significantly reduced in the first 3 months after LASIK (p<0.001).

Related Experiment Videos

  • Tear secretion returned to baseline values by 9 months post-surgery.
  • Preoperative long-term contact lens wear was associated with more pronounced reductions in tear secretion and sensitivity up to 6 months post-surgery (p<0.05).

    • Conclusions:

    • LASIK leads to a depression in tear secretion for at least 6 months post-surgery.
    • Corneal sensitivity also shows a significant reduction in the initial postoperative period.