Related Experiment Video
Updated: Jul 26, 2026

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
Published on: January 5, 2017
The medical management of acute and chronic ulcerative colitis
1Division of Gastroenterology Box #1069, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.
Abstract:
The current medical therapy of severe, acute ulcerative colitis is reviewed. The role and of 5-ASA, corticosteroids, immunosuppressive agents and surgery are outlined. A systematic approach using a combination of these agents to induce a remission is presented. A model for long term maintenance therapy following a response in the acute setting to avoid steroid dependence and surgery is proposed. The role of surgery in ulcerative colitis should be limited to patients who either fail medical therapy or in whom dysplasia or cancer have been detected. A realistic assessment of the potential pitfalls of surgical intervention, such as ileal pouch-anal anastomosis, is discussed.
Related Concept Videos
Drugs for Treatment of Ulcerative Colitis in IBD
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease II: Ulcerative Colitis

