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Eye-wall resection.

D H Char1, T Miller, J B Crawford

  • 1Tumori Eye Foundation, San Francisco, California, USA.

Transactions of the American Ophthalmological Society
|February 24, 2001
PubMed
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Eye-wall resection successfully retained 70% of eyes with uveal tumors, achieving good visual acuity in 56%. Metastatic disease occurred in only 7% of uveal melanoma patients, suggesting this technique is a viable option.

Area of Science:

  • Ophthalmology
  • Oncology
  • Surgical Pathology

Background:

  • Uveal tumors, including melanomas, pose a significant challenge in ocular oncology.
  • Eye-wall resection is a surgical technique employed for managing these tumors.
  • Assessing the outcomes of eye-wall resection is crucial for patient management.

Purpose of the Study:

  • To evaluate ocular retention rates after eye-wall resection for uveal tumors.
  • To determine the visual outcomes and metastatic rates in patients undergoing this procedure.
  • To analyze the efficacy of eye-wall resection techniques in managing uveal tumors.

Main Methods:

  • Retrospective analysis of 132 eyes with uveal tumors undergoing eye-wall resection by a single surgeon.
  • Histologic review of enucleation specimens.

Related Experiment Videos

  • Parametric and non-parametric data analysis.

    • Main Results:

    • 70% of eyes (93/132) were retained post-surgery.
    • 56% of retained eyes achieved a final visual acuity of 20/40 or better.
    • Metastatic disease developed in 7% of uveal melanoma patients, primarily in those with choroidal involvement.

    Conclusions:

    • Eye-wall resection is a viable option for uveal tumor management, with high ocular retention and favorable visual outcomes.
    • The technique appears to have a low risk of metastatic disease in uveal melanoma.
    • Ocular retention and visual results may be superior to radiation alone for thick, posterior uveal melanomas.