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Related Experiment Videos

Uveal tumour resection.

D H Char1, T Miller, J B Crawford

  • 1The Tumori Eye Foundation, CPMC Davies, Stanford University, CA 94114, USA. devron@tumori.org

The British Journal of Ophthalmology
|September 25, 2001
PubMed
Summary
This summary is machine-generated.

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Eye wall resection successfully retained 76% of eyes with uveal tumors, achieving good vision in over half. Metastasis rates were low, suggesting this technique is a viable option for ocular tumor management.

Area of Science:

  • Ophthalmology
  • Oncology
  • Surgical Pathology

Background:

  • Uveal tumors, particularly melanomas, pose a significant challenge in ocular oncology.
  • Eye wall resection is a surgical technique employed for managing these tumors, aiming for both tumor removal and globe preservation.
  • Assessing the outcomes of this technique is crucial for guiding treatment decisions.

Purpose of the Study:

  • To evaluate ocular retention rates following eye wall resection for uveal tumors.
  • To determine the visual acuity outcomes in eyes managed with this technique.
  • To investigate the incidence of metastases after eye wall resection for uveal tumors.

Main Methods:

  • Retrospective analysis of consecutive local uveal tumor resections performed by a single surgeon.

Related Experiment Videos

  • Histopathological review of enucleation specimens.
  • Parametric and non-parametric statistical analysis of collected data.

    • Main Results:

    • 138 eyes underwent eye wall resection, with 76% (105 eyes) successfully retained.
    • 53% of retained eyes achieved a final visual acuity of 20/40 or better, with better outcomes for anteriorly located tumors.
    • Eight patients (approximately 7%) developed metastases, primarily in those with posterior, choroidal melanomas.

    Conclusions:

    • Eye wall resection is an effective method for retaining eyes with uveal tumors, with a significant proportion achieving good visual acuity.
    • The technique appears to have a low rate of metastatic disease development.
    • Ocular retention and visual results may be superior with eye wall resection compared to radiation therapy alone, especially for thick, posterior melanomas.