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Tetraoxygenated naturally occurring xanthones.

V Peres1, T J Nagem, F F de Oliveira

  • 1Departamento de Química, Universidade Federal de Viçosa, Minas Gerais, Brazil.

Phytochemistry
|February 24, 2001
PubMed
Summary

This review explores naturally occurring tetraoxygenated xanthones from plants, fungi, and lichens. It details their chemical structures, distribution, and potential pharmacological activities for therapeutic applications.

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Area of Science:

  • Natural Product Chemistry
  • Phytochemistry
  • Pharmacognosy

Background:

  • Xanthones are a significant class of natural products.
  • Tetraoxygenated xanthones are found across diverse plant families.
  • These compounds have shown promising biological activities.

Purpose of the Study:

  • To comprehensively review naturally occurring tetraoxygenated xanthones.
  • To document their chemical structures and natural sources.
  • To explore their pharmacological relevance and therapeutic potential.

Main Methods:

  • Literature review of 350 references.
  • Compilation of data on 234 identified tetraoxygenated xanthones.
  • Analysis of chemical structures and plant/fungal/lichen distribution.

Main Results:

  • Detailed information on 234 tetraoxygenated xanthones from 182 plant species, fungi, and lichens.
  • Structural formulas and distribution data for 135 isolated compounds.
  • Summary of pharmacological activities and therapeutic uses.

Conclusions:

  • Tetraoxygenated xanthones represent a rich area of natural product research.
  • These compounds hold significant potential for drug discovery and development.
  • Further investigation into their biological activities is warranted.

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