Related Experiment Video
Updated: Jan 25, 2026

Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity
Published on: June 16, 2022
Bayesian methods for a growth-curve degradation model with repeated measures
1Department of Mathematics and Statistics, University of Surrey, Guildford, GU2 5XH, Surrey, U.K.
Abstract:
The increasing reliability of some manufactured products has led to fewer observed failures in reliability testing. Thus, useful inference on the distribution of failure times is often not possible using traditional survival analysis methods. Partly as a result of this difficulty, there has been increasing interest in inference from degradation measurements made on products prior to failure. In the degradation literature inference is commonly based on large-sample theory and, if the degradation path model is nonlinear, their implementation can be complicated by the need for approximations. In this paper we review existing methods and then describe a fully Bayesian approach which allows approximation-free inference. We focus on predicting the failure time distribution of both future units and those that are currently under test. The methods are illustrated using fatigue crack growth data.
Related Concept Videos
Microbial Growth Measurement: Indirect Methods
Microbial Growth Measurement: Direct Methods
Bacterial Growth Curve
Proteins: From Genes to Degradation
Transcription is the synthesis of RNA...
Regulated Protein Degradation
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
Regulated Protein Degradation

