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[Tin compounds in pharmacy and nutrition]
1Szegedi Tudományegyetem, Szervetlen és Analitikai Kémia Tanszék, Szeged.
Summary
Tin is beneficial for living organisms, though not essential. This review covers tin
Area of Science:
- Environmental Chemistry
- Biochemistry
- Toxicology
Context:
- Tin's natural abundance in Earth's lithosphere and hydrosphere.
- Formation of diverse tin(II) and tin(IV) complexes.
- Investigating tin's role in biological systems.
Purpose:
- To evaluate the essentiality and beneficial effects of tin for living species.
- To detail the chemistry and toxicity of tin compounds in humans and animals.
- To review the pharmaceutical applications of tin.
Summary:
- Tin is found in plants, animals, and humans, with various tin(II) and tin(IV) complexes.
- Evidence suggests tin is beneficial, though not definitively essential.
- Tin compounds exhibit toxicity, but also have pharmaceutical uses, including anticancer agents.
Impact:
- Provides a comprehensive overview of tin's biological significance and toxicity.
- Highlights current and potential therapeutic applications of tin-based drugs.
- Informs research on tin's role in health and disease.