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Metastatic carcinoma simulating inflammatory colitis.

M A Meyers, M Oliphant, H Teixidor

The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine

|January 1, 1975

Summary

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Metastatic colon cancer can mimic inflammatory bowel disease like Crohn's disease on imaging. Recognizing specific roentgen features aids in differentiating metastatic disease from colitis, crucial for patient management.

Area of Science:

Gastroenterology
Radiology
Oncology

Background:

Metastatic carcinoma in the colon can be misdiagnosed as inflammatory colitis.
This misdiagnosis can occur both clinically and through radiological examinations, particularly mimicking Crohn's disease.

Purpose of the Study:

To identify and establish the distinctive roentgenologic features of metastatic disease to the colon.
To differentiate metastatic colon cancer from inflammatory colitis based on imaging characteristics.

Main Methods:

Analysis of roentgenologic findings in 12 cases of metastatic colon disease.
Correlation of imaging features with pathways of spread, tumor growth, and local tissue response.

Main Results:

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Characteristic changes include mucosal thickening, nodular masses, eccentric strictures, asymmetric involvement, pseudosacculations, and contour spiculations.

These roentgen features are dependent on the route of metastasis, tumor biology, and host response.

Conclusions:

Distinctive roentgenologic features can identify metastatic disease to the colon.
Accurate differential diagnosis is vital for patients presenting with symptoms of colitis, especially those with known or occult primary malignancies.