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Updated: Aug 15, 2026

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
Published on: March 3, 2014
Polyferredoxin-based electrode materials
C J Pickett1, S K Ibrahim, D L Hughes
1Department of Biological Chemistry, John Innes Centre, Norwich, UK NR4 7UH.
Abstract:
Electrochemical oxidation of the hydrosulfide cluster [Fe4S4(SH)4]2- on gold, platinum or vitreous carbon in a methyl cyanide electrolyte leads to the growth of a conducting film. Spectroscopic and other evidence suggests that the film has cubane centres, predominately in the [4Fe4S]3+ oxidation state, which are linked by disulfide ligands to give an anionic array of [Fe4S4(S approximately)4]n- units. X-ray data suggests some long-range order in the electrode material. The polyferredoxin binds redox active cations consistent with an anionic array.
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