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Updated: Aug 13, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Published on: May 8, 2016
[Pathogenetic and morphological characteristics of acute inflammation of the central nervous system]
1St-Petersburg Medical Pediatric Academy, 194100, St-Petersburg.
Abstract:
Virus, bacteria, mycoplasma, protozoa can be the causes of acute neuroinfections. The agents can penetrate into the brain by blood, nerve, lymphatic vessels, from the sinuses directly. Peculiarities of manifestations of acute neuroinfections depend on the agent tropism to receptors of nervous cell and specificity of brain immunoreactivity. The brain injuries can be induced by microorganism action or through immunopathologic processes. Dynamics of morphological changes in acute neuroinfections of different etiology are summarized. Histological, cytological, bacteriological, serological, immunofluorescent, histochemical methods are evaluated. Acute neuroinfection pathogenesis has many unresolved problems.
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