Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Precocious noduloulcerative cutaneous syphilis.

H Pariser

    Archives of Dermatology
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Noduloulcerative lesions during secondary syphilis, without systemic signs, challenge traditional classifications. Researchers suggest replacing "malignant" syphilis with "non-noduloulcerative cutaneous syphilis" for accuracy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Norfolk faces an issue; a progress report on social hygiene efforts in a war congested area.

    Journal of social hygiene·2010
    Same author

    A proposed clerical system for a city venereal disease control program.

    American journal of syphilis, gonorrhea, and venereal diseases·2010
    Same author

    Syphilis.

    Primary care·1989
    Same author

    Analysis of a recent epidemic due to penicillinase-producing Neisseria gonorrhoeae: epidemiologic and medical considerations.

    Sexually transmitted diseases·1982
    Same author

    Asymptomatic gonorrhea.

    Cutis·1976
    Same author

    Treatment of gonorrhea with minocycline.

    Southern medical journal·1975

    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Syphilology

    Background:

    • Syphilis is a complex sexually transmitted infection caused by *Treponema pallidum*.
    • The secondary stage of syphilis can present with diverse mucocutaneous manifestations.
    • The term 'malignant syphilis' has been used for severe, ulcerative forms, but its precise definition and utility are debated.

    Purpose of the Study:

    • To describe a case of widespread, noduloulcerative syphilitic lesions occurring during the secondary stage.
    • To evaluate the diagnostic findings in a patient with atypical secondary syphilis presentation.
    • To propose a revised terminology for severe cutaneous syphilis presentations.

    Main Methods:

    • Clinical case presentation and detailed lesion description.

    Related Experiment Videos

  • Diagnostic workup including darkfield microscopy and cerebrospinal fluid analysis.
  • Review of syphilis staging and terminology in medical literature.

    • Main Results:

    • A patient presented with extensive noduloulcerative lesions consistent with secondary syphilis.
    • No systemic manifestations of syphilis were noted, apart from possible periostitis.
    • Darkfield examination and cerebrospinal fluid analysis for *Treponema pallidum* were negative.
    • The clinical presentation did not align with typical descriptions of severe or 'malignant' syphilis.

    Conclusions:

    • The case highlights the variability of cutaneous manifestations in secondary syphilis.
    • The term 'malignant' syphilis may be misleading and should be reconsidered.
    • The authors propose 'non-noduloulcerative cutaneous syphilis' as a more accurate descriptor for such presentations.