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[Primary hyperparathyroidism in pregnancy--a case report].

B Karbowski1, U Bock-Steinweg

  • 1St. Johannes Hospital Dortmund.

Zeitschrift Fur Geburtshilfe Und Neonatologie
|February 24, 2001
PubMed
Summary

Primary hyperparathyroidism in pregnancy is rare but can cause neonatal hypocalcemia. Surgical removal of parathyroid adenoma is crucial for reducing maternal and fetal complications.

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Area of Science:

  • Endocrinology
  • Obstetrics
  • Nephrology

Background:

  • Primary hyperparathyroidism (PHP) is uncommon in pregnancy, affecting approximately 8 per 100,000 women of childbearing age.
  • Physiological calcium metabolism changes during pregnancy can mask PHP symptoms.

Observation:

  • A case report details a 33-year-old pregnant woman diagnosed with PHP post-delivery due to neonatal hypocalcemia.
  • The patient had a history of recurrent urinary tract infections and left-sided hydronephrosis, later diagnosed with nephrolithiasis.

Findings:

  • A parathyroid adenoma was identified as the cause of PHP and successfully removed.
  • Neonatal hypocalcemia was the presenting symptom, indicating significant calcium imbalance.

Implications:

  • Considering PHP in pregnant women with hydronephrosis is vital for early diagnosis and intervention.
  • Timely surgical management of parathyroid adenoma significantly lowers maternal and fetal morbidity and mortality rates.

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