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Migraine associated with menstruation.

A MacGregor1

  • 1City of London Migraine Clinic and St Bartholomew's Hospital, London, UK.

Functional Neurology
|February 24, 2001
PubMed
Summary
This summary is machine-generated.

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Menstrual migraine, often occurring around day 1 of the cycle, may be less responsive to standard treatments. Perimenstrual prophylaxis and hormone therapy offer targeted management options for this common headache type.

Area of Science:

  • Neurology
  • Gynecology
  • Pharmacology

Background:

  • Many women experience increased migraine frequency linked to menstruation.
  • The term 'menstrual' migraine lacks a universally agreed-upon definition.
  • Migraine prevalence increases around day 1 +/- 2 of the menstrual cycle, typically without aura.

Purpose of the Study:

  • To define and discuss the management strategies for menstrual migraine.
  • To review current treatment approaches, including acute and prophylactic therapies.
  • To explore the role of hormonal fluctuations and therapies in menstrual migraine.

Main Methods:

  • Review of existing literature and classifications by the International Headache Society.
  • Analysis of proposed definitions based on cyclical migraine patterns.

Related Experiment Videos

  • Evaluation of therapeutic responses to acute and prophylactic treatments, including hormonal interventions.
  • Main Results:

    • Menstrual migraine attacks may be less responsive to standard acute treatments.
    • Perimenstrual prophylaxis is effective if the menstrual link is confirmed over three cycles.
    • NSAIDs, transdermal oestrogens, and depot progestogens are recommended treatments; oral progestogens are less effective.

    Conclusions:

    • Effective management requires accurate diagnosis and tailored treatment strategies.
    • Hormone therapy, particularly non-oral oestrogen delivery, can be beneficial for menopausal women with migraine.
    • Optimizing hormone therapy, considering route and dose, is crucial to control migraine and menopausal symptoms.