Coexistent adenoviral keratoconjunctivitis and Acanthamoeba keratitis
Related Experiment Video
Updated: Oct 9, 2026

Quantification of Acanthamoeba spp. Motility
Published on: September 20, 2024
A D Gajdatsy1, A Kosmin, G D Barrett
1Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. gajdatsy@global.net.au
Abstract:
A 17-year-old youth presented with bilateral follicular conjunctivitis and nummular subepithelial corneal infiltrates. Failure of this to settle in an outpatient setting led to corneal scraping with microscopy and culturing for bacteria, fungi, Herpes simplex, adenovirus and Acanthamoeba as an inpatient. Polymerase chain reaction analysis of corneal cells was positive for adenovirus, and culture on live Escherichia coli-coated agar plates was positive for Acanthamoeba by phase contrast microscopy on day two. We conclude that Acanthomoeba infection can complicate adenoviral keratoconjunctivitis. This observation is in keeping with previously reported modes of infection by Acanthamoeba, whereby any epithelial breach seems to allow inoculation of the eye by this opportunistic organism.
More Related Videos
11:13Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
Published on: April 7, 2016
07:50A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Related Concept Videos
Microbiome of the Eye
Cytomegalovirus Disease
Angle Closure Glaucoma: Treatment
Candidiasis
Glaucoma: Overview
Cryptococcal Meningitis