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Updated: Oct 9, 2026
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Use of a Caspase Multiplexing Assay to Determine Apoptosis in a Hypothalamic Cell Model
Published on: April 16, 2014
[Morphological estimation of apoptosis in preclinical studies of new drugs]
G V Karpova1, E A Timina, M R Karpova
1Institute of Pharmacology, Tomsk Scientific Center, Siberian Division, Russian Academy of Medical Sciences, pr. Lenina 3, Tomsk, 634028 Russia.
Eksperimental'Naia I Klinicheskaia Farmakologiia
|February 24, 2001
Abstract:
A method for morphological estimation of the thymus cell loss during apoptosis proposed, which can be used as a screening test in the stage of preclinical characterization of new biologically active compounds. Efficacy of the proposed method is demonstrated by evaluating the degree of apoptosis-inducing effect of some antitumor preparations.
