Related Experiment Videos
Structure-activity relationships for the analgesic activity of gallic acid derivatives
R Krogh1, R A Yunes, A D Andricopulo
1College of Pharmacy, University of Michigan, Ann Arbor 48109, USA.
Farmaco (Societa Chimica Italiana : 1989)
|February 24, 2001
Abstract:
Values of ID50 for a collection of structurally-related gallic acid derivatives have been employed to create a predictive quantitative structure-activity relationship (QSAR) which links structure to values of analgesic activity. The QSAR model developed has substantial predictive power for the design of novel gallic acid derivatives having improved analgesic potency.