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Cannabis arteritis revisited--ten new case reports
P Disdier1, B Granel, J Serratrice
1Service de Médecine Interne, CHU de la Timone, Marseille, France. pdisdier@ap-hm.fr
Angiology
|February 24, 2001
Summary
Cannabis arteritis, a severe vascular disease, affects young adults with limb ischemia and gangrene. Prolonged cannabis use may be an additive risk factor, necessitating searches for cannabis use in young smokers with arteritis.
Area of Science:
- Vascular Surgery
- Toxicology
- Cardiology
Background:
- Cannabis arteritis, first described in the 1960s, is a rare occlusive vascular disease.
- Young adults are increasingly presenting with severe limb ischemia and gangrene.
Purpose of the Study:
- To revisit the concept of cannabis arteritis.
- To report 10 new cases of cannabis arteritis in young male patients.
Main Methods:
- Case series reporting on 10 male patients with subacute distal limb ischemia.
- Clinical evaluation, biological tests, and arteriographic assessment.
- Review of patient history regarding tobacco smoking and cannabis use.
Main Results:
- Ten male patients (median age 23.7 years) developed distal limb ischemia, necrosis, and gangrene.
- Arteriography revealed distal arterial abnormalities resembling Buerger's disease.
- All patients were moderate tobacco smokers and regular cannabis users; five amputations were required.
Conclusions:
- Prolonged cannabis use may be an additive risk factor for juvenile and young adult arteritis.
- Cannabis arteritis is a severe, forgotten occlusive vascular disease.
- Screening for cannabis use is crucial for understanding arteritis in young smokers.
