Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Base Pairing02:27

DNA Base Pairing

Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
DNA Base Pairing02:27

DNA Base Pairing

Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
DNA Helicases00:55

DNA Helicases

DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
DNA Topoisomerases02:02

DNA Topoisomerases

Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types.  Type I...
DNA-only Transposons02:57

DNA-only Transposons

DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paramagnetic Singularities of the Orbital Magnetism in Graphene with a Moiré Potential.

Physical review letters·2023
Same author

Visualization of G-Quadruplexes, i-Motifs and Their Associates.

Acta naturae·2022
Same author

Detection of graphene's divergent orbital diamagnetism at the Dirac point.

Science (New York, N.Y.)·2021
Same author

Collapse of the Josephson Emission in a Carbon Nanotube Junction in the Kondo Regime.

Physical review letters·2021
Same author

Spin-Orbit-Enhanced Robustness of Supercurrent in Graphene/WS_{2} Josephson Junctions.

Physical review letters·2021
Same author

[Biomarkers of system inflammation in local and diffuse peritonitis].

Biomeditsinskaia khimiia·2020
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

Associated Chromosome Trap for Identifying Long-range DNA Interactions
14:49

Associated Chromosome Trap for Identifying Long-range DNA Interactions

Published on: April 23, 2011

Proximity-induced superconductivity in DNA.

A Y Kasumov1, M Kociak, S Guéron

  • 1Laboratoire de Physique des Solides, Associé au CNRS, Bât 510, Université Paris-Sud, 91405, Orsay, France.

Science (New York, N.Y.)
|February 24, 2001
PubMed
Summary
This summary is machine-generated.

Double-stranded DNA exhibits ohmic conductivity down to 1 Kelvin. DNA molecules maintain phase coherence over hundreds of nanometers, even at millikelvin temperatures, suggesting potential as molecular wires.

More Related Videos

CD Spectroscopy to Study DNA-Protein Interactions
06:48

CD Spectroscopy to Study DNA-Protein Interactions

Published on: February 10, 2022

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast
09:19

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast

Published on: March 6, 2026

Related Experiment Videos

Last Updated: Jun 24, 2026

Associated Chromosome Trap for Identifying Long-range DNA Interactions
14:49

Associated Chromosome Trap for Identifying Long-range DNA Interactions

Published on: April 23, 2011

CD Spectroscopy to Study DNA-Protein Interactions
06:48

CD Spectroscopy to Study DNA-Protein Interactions

Published on: February 10, 2022

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast
09:19

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast

Published on: March 6, 2026

Area of Science:

  • Molecular electronics
  • Condensed matter physics
  • Nanotechnology

Background:

  • Understanding the electrical properties of DNA is crucial for molecular electronics.
  • Previous studies have explored DNA conductivity with varying results.
  • Investigating DNA behavior at cryogenic temperatures is essential for its application in quantum devices.

Purpose of the Study:

  • To measure the conductivity of double-stranded DNA molecules at cryogenic temperatures.
  • To determine the ohmic behavior and resistance of DNA over a wide temperature range.
  • To investigate proximity-induced superconductivity in DNA.

Main Methods:

  • DNA molecules were deposited using a combing process across a submicron slit.
  • Conductivity measurements were performed between rhenium/carbon metallic contacts.
  • Measurements were conducted from room temperature down to 1 Kelvin.

Main Results:

  • DNA conduction was found to be ohmic between room temperature and 1 Kelvin.
  • The resistance per DNA molecule was less than 100 kilohm and showed weak temperature dependence.
  • Proximity-induced superconductivity was observed below the superconducting transition temperature of the contacts.

Conclusions:

  • DNA molecules can conduct electricity down to millikelvin temperatures.
  • Phase coherence is maintained over several hundred nanometers in DNA molecules.
  • These findings support the potential of DNA as a component in cryogenic electronic devices.