[Effect of dilren on hemodynamics of patients with essential hypertension]

Changes in hemodynamics and circadian rhythms in the course of dilren-300 treatment were studied in 20 patients with hypertension stage II. Tetrapolar chest rheography, echo-CG, ECG, measurements of arterial pressure by N. S. Korotkov were made 6 times a days (at 2, 6, 10 a.m. and 2, 6, 10 p.m.). The information was processed statistically. Dilren -300, administered at 8.00 a.m. for 10 days, had a hypotensive, vasodilating and weak negative chronotropic effect. The drug reduced myocardial energy consumption, eliminated circadian rhythms of heart rate, arterial pressure, cardiac performance and others observed before the treatment.