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Updated: Aug 19, 2026

Cytosolic Calcium Measurements in Renal Epithelial Cells by Flow Cytometry
Published on: October 28, 2014
Hypocalcemic syndromes
1Department of Medical Science, Uppsala University, Uppsala, Sweden. fredrik.carlstedt@post.utfors.se
Abstract:
Hypocalcemia is common in the ICU and is a marker of poor prognosis. The mechanisms behind the low calcium levels include extravasation, increased chelation, intracellular overload of calcium, and an altered parathyroid hormone (PTH) secretion. Hypocalcemia and an altered PTH secretion seem to be related to systemic inflammation, but it is not known today if this response is appropriate or not. Therefore, a general supplementation with calcium in these patients cannot be recommended at this stage.
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