Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Venezuelan equine encephalomyelitis.

R Rico-Hesse1

  • 1Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas, USA.

The Veterinary Clinics of North America. Equine Practice
|February 24, 2001
PubMed
Summary

Epidemic Venezuelan equine encephalitis (VEE) viruses continue to emerge due to high mutation rates. Future vaccines should target enzootic viruses to prevent VEE virus transmission at its source.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dengue virus virulence and transmission determinants.

Current topics in microbiology and immunology·2009
Same author

Differential susceptibility of Aedes aegypti to infection by the American and Southeast Asian genotypes of dengue type 2 virus.

Vector borne and zoonotic diseases (Larchmont, N.Y.)·2003
Same author

Hepadnavirus infection in captive gibbons.

Journal of virology·2000
Same author

Dengue virus structural differences that correlate with pathogenesis.

Journal of virology·1999
Same author

[Serotypes and genotypes of dengue virus circulating in Venezuela, 1990-1997].

Acta cientifica venezolana·1999
Same author

Association of Venezuelan equine encephalitis virus subtype IE with two equine epizootics in Mexico.

The American journal of tropical medicine and hygiene·1998

Area of Science:

  • Virology
  • Epidemiology
  • Vaccinology

Background:

  • Epidemic Venezuelan equine encephalitis (VEE) viruses emerge due to high RNA virus mutation rates.
  • Current vaccines are effective against VEE in equids but not in human epidemics.
  • VEE virus occurrences in Mexico indicate current vaccines do not interrupt transmission from enzootic cycles.

Purpose of the Study:

  • To evaluate the effectiveness of current VEE virus vaccines.
  • To propose a new vaccine strategy targeting enzootic VEE viruses.

Main Methods:

  • Analysis of VEE virus emergence patterns.
  • Review of vaccine efficacy data in equids and humans.
  • Assessment of VEE virus transmission cycles.

Main Results:

  • High mutation rates of VEE viruses contribute to epidemic emergence.
  • Existing vaccines are insufficient to prevent VEE virus transmission from enzootic sources.
  • Recent VEE outbreaks suggest vaccine limitations.

Conclusions:

  • Current VEE vaccines do not interrupt transmission at the source.
  • Future VEE vaccines should utilize immunogens from enzootic viruses.
  • Targeting enzootic cycles is crucial for preventing VEE virus emergence.

Related Experiment Videos