Related Experiment Video
Updated: Oct 9, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
The influence of traumatic brain lesion on sleep architecture
1Neurological Clinic, 1st Medical Faculty of Charles University, Katerinska 30, 120 00 Prague, Czech Republic.
Abstract:
The authors deal with sleep changes in patients after brain injury. Ten patients were examined with the use of daytime routine EEG and night polysomnography. The amount of REM sleep is most sensitive to brain damage and is reduced in all patients with nonspecific epileptiform changes in the EEG. Changes in deep synchronous sleep are less frequent and are not in correlation with the prevalence of epileptiform changes. Thus the reduction of REM sleep seems to be a sensitive marker of development of epileptiform EEG-changes and perhaps could play a predictive role of development of post-traumatic epilepsy.
Related Concept Videos
Traumatic Brain Injury l: Introduction
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
REM Sleep Behavior Disorder
RBD is significantly associated with...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
