Related Experiment Video
Updated: Oct 9, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
Intravenous nutrition in critical illness
Paul Kitchen1, Alastair Forbes
1St Mark's Hospital and Academic Institute, Harrow, UK.
Abstract:
Our understanding of the effects of total parenteral nutrition in critical illness has been refined over the past year. The importance of not overfeeding patients has been highlighted. The effects of lipid emulsions containing medium-chain triglycerides, compared with standard ones, have been investigated and show, in particular, changes in platelet membrane fatty acid composition. Although data on clinical end-points are lacking, this is likely to be a fruitful area of further research. The importance of providing enteral support, if at all possible, has been further underlined by its beneficial effects on bile composition in the intensive care setting. Finally, critical illness has been shown to be, in general, a contraindication to growth hormone therapy.
Related Concept Videos
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Acute Kidney Injury VI: Nursing Management
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Acute Kidney Injury V: Interprofessional Care