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Published on: February 18, 2015
Chronic mucocutaneous candidiasis
1Department of Medicine, University of Colorado Health Sciences Center, Denver 80206-1210, USA. ckirkpatrick@eri.uchsc.edu
Abstract:
Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions. A common immunologic abnormality is failure of the patient's T lymphocytes to produce cytokines that are essential for expression of cell-mediated immunity to Candida. Antifungal drugs are effective in clearing the infections, and treatments that restore cellular immunity have produced long term remissions.
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