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Perinatal herpes simplex infection presenting with pneumonia and pleural effusions
1Department of Pediatrics, Texas Tech University Health Sciences Center School of Medicine, Odessa 79763, USA. pedoreb@tthsc8.odessa.ttuhsc.edu
A rare perinatal herpes infection case showed pneumonia and pleural effusions in a newborn. This highlights the diverse presentations of neonatal herpes simplex virus infections.
Area of Science:
- Neonatology
- Infectious Diseases
- Pediatric Pulmonology
Background:
- Perinatal herpes simplex virus (HSV) infection is a serious neonatal condition.
- Early diagnosis and treatment are crucial for improving outcomes.
- Typical presentations include skin, eye, and mouth lesions, or disseminated disease.
Observation:
- This report details an unusual case of perinatal herpes infection.
- The neonate presented with atypical symptoms of pneumonia and pleural effusions.
- No characteristic skin, eye, or mouth lesions were initially observed.
Findings:
- Herpes simplex virus was identified as the causative agent.
- The presentation mimicked other neonatal respiratory infections.
- Pulmonary involvement with pleural effusions is an uncommon manifestation of neonatal HSV.
Implications:
- This case underscores the importance of considering neonatal HSV infection in newborns with unexplained pneumonia and respiratory distress.
- Broadening the differential diagnosis for neonatal respiratory illness is essential.
- Prompt diagnostic workup, including viral PCR, is critical for timely management of atypical presentations.
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