Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alcohol-induced liver disease.

W C Maddrey1

  • 1Department of Internal Medicine, University of Texas Medical Center at Dallas, Dallas, Texas, USA.

Clinics in Liver Disease
|March 10, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Severe hepatitis from methyldopa.

Gastroenterology·2012
Same author

Adult hepatitis B vaccination using a novel triple antigen recombinant vaccine.

Hepatology (Baltimore, Md.)·2001
Same author

Comparison of a triple antigen and a single antigen recombinant vaccine for adult hepatitis B vaccination.

Journal of medical virology·2001
Same author

A multi-center controlled study of rapid hepatitis B vaccination using a novel triple antigen recombinant vaccine.

Vaccine·2001
Same author

The hepatic safety and tolerability of the novel cyclooxygenase-2 inhibitor celecoxib.

American journal of therapeutics·2001
Same author

A model for a managed care education approach to increase hepatitis awareness: Part I.

Managed care interface·2001
Same journal

Metabolic Dysfunction-Associated Steatohepatitis: From Fibrosis-Based Risk Stratification to Emerging Therapeutic Strategies.

Clinics in liver disease·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease and Viral Hepatitis.

Clinics in liver disease·2026
Same journal

Metabolic Dysfunction Associated Steatohepatitis (MASH) in Oceania, Central America, and the Caribbean.

Clinics in liver disease·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease in Latin America.

Clinics in liver disease·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease in Africa: From Burden to Action.

Clinics in liver disease·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease in Asia: Epidemiology, Clinical Features, and Management.

Clinics in liver disease·2026
See all related articles

Regular alcohol consumption can cause liver damage, including cirrhosis, with women being more susceptible. Co-infection with hepatitis C significantly worsens liver disease progression in alcoholics.

Area of Science:

  • Hepatology
  • Toxicology

Background:

  • Regular alcohol ingestion leads to various hepatic changes like fat infiltration, alcoholic hepatitis, and cirrhosis.
  • Only 10-15% of chronic alcoholics develop liver disease, with women showing increased susceptibility.
  • Concomitant infection with hepatitis C virus is prevalent in chronic alcoholics and exacerbates liver injury.

Purpose of the Study:

  • To highlight the significant impact of alcohol on liver health.
  • To emphasize the synergistic negative effect of hepatitis C co-infection on alcohol-induced liver disease.
  • To discuss potential therapeutic interventions for severe alcoholic hepatitis.

Main Methods:

  • Review of existing literature on alcohol-induced liver disease.
  • Analysis of epidemiological data on chronic alcoholics and hepatitis C co-infection.

Related Experiment Videos

  • Evaluation of treatment outcomes for alcoholic hepatitis.

    • Main Results:

    • Alcoholic liver disease encompasses fat infiltration, alcoholic hepatitis, and cirrhosis.
    • Hepatitis C co-infection dramatically increases the risk of progressive liver disease and cirrhosis.
    • Corticosteroid therapy demonstrates efficacy in severe acute alcoholic hepatitis.

    Conclusions:

    • Alcohol abuse is a major cause of liver disease.
    • Hepatitis C and alcohol co-infection represent a critical public health concern requiring targeted management.
    • Effective treatment strategies, including corticosteroids for severe cases, are crucial for managing alcoholic hepatitis.