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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[A case of squamous cell carcinoma of the bladder that was successfully treated with multidisciplinary therapies]
S Matsumoto1, T Nishioka, T Akiyama
1Department of Urology, Sakai Hospital, Kinki University School of Medicine.
Abstract:
A 45-year-old man with hematopyuria detected at another hospital visited our department for further examination. Endoscopic examination revealed a disintegration abscess between the bladder neck and prostatic urethra. Transurethral biopsy demonstrated squamous cell carcinoma of the bladder. He received 40 Gy of radiation combined with M-VAC (methotrexate, vinblastine, dovorubicin cisplatin) chemotherapy. Pathologically, a complete response was found when he underwent total cystourethrectomy. There has been no sign of recurrence for one and a half years postoperatively.