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[Effects of chronic stress on the learning and memory ability and hippocampal LTP in rats]
Abstract
Aim And Methods:
A chronic stress model in 21 days with multi-stressors was applied to question the effects of stress on the learning and memory ability and the hippocampal neuronal synaptic plasticity in rats, using the Y maze test and LTP electrophysiological recording in vivo.
Results:
The impairment of spatial learning and memory ability and an obvious suppression in LTP in hippocampal dentate gyrus was observed in stress group after chronic stress.
Conclusion:
The hippocampal synaptic plasticity may be decreased by the chronic stress. And then, the learning and memory ability may also be impaired consequently.