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[Analysis on genetic polymorphism of mtDNA in endurance athletes and sedentary subjects]
Aim:
To analysis the sequence variation of the origin region (D-loop) of mitochondrial DNA (mtDNA) in elite endurance athletes and sedentary subjects in order to find the genetic markers related with performance.
Methods:
Using a new established PCR method by virtue of tracing sample analysis, the restricted fragment length polymorphism (RFLP) of D-loop in mtDNA was assessed in 76 elite Chinese endurance athletes (EEA), 33 endurance athletes with average-level(GEA) and 20 sedentary control(sc).
Results:
There is a significant difference in distribution of the polymorphism in mtDNA D-loop between the EEA and SC(chi 2 = 33.3, P < 0.01).
Conclusion:
The sequence variation of D-loop region of mtDNA in the elite endurance athletes may contribute to the individual difference in aerobic performance and trainability.