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Updated: Jul 27, 2026

Presynaptic Dopamine Dynamics in Striatal Brain Slices with Fast-scan Cyclic Voltammetry
Published on: January 12, 2012
[Monitoring dopamine release by fast cyclic voltammetry: an in vivo study]
1Department of Physiology, Medical College of Qingdao University, Qingdao 266021.
Aim And Methods:
Using fast cyclic voltammetry (FCV) and carbon fibre microelectrode (CFMe), we monitored dopamine (DA) release from caudate putamen(CPu), nucleus accumbens(Acb) and central amygdaloid nucleus(CAN) of normal rats in vivo, in order to find out the suitable parameters to evoke DA release of certain area. DA release was evoked by electrical stimulation of medial forebrain bundle(MFB) or ventral tegmental area(VTA).
Results:
DA release from CPu, Acb or CAN were different in contents and the characteristics of dynamics.
Conclusion:
Different parameters should be used according to the different sites of stimulation in order to get the maximal DA release during the experiment.
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