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Lower eyelid CO(2) laser rejuvenation: a randomized, prospective clinical study
S R Carter1, S R Seiff, P H Choo
1Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA.
Ophthalmology
|March 10, 2001
Summary
Transconjunctival blepharoplasty alone improved lower lid bulging but worsened wrinkles. Combining it with CO(2) laser resurfacing significantly improved wrinkles, offering a scarless alternative for lower lid rejuvenation.
Area of Science:
- Oculoplastic surgery
- Dermatologic surgery
- Cosmetic surgery
Background:
- Lower eyelid aging presents challenges with bulging and wrinkles.
- Transconjunctival blepharoplasty addresses fat herniation but not skin quality.
- CO2 laser resurfacing can improve skin texture and wrinkles.
Purpose of the Study:
- To compare transconjunctival blepharoplasty alone versus combined with CO2 laser resurfacing for lower lid aesthetics.
- To evaluate the impact on lower lid bulging and wrinkles.
- To assess the timing of CO2 laser resurfacing relative to blepharoplasty.
Main Methods:
- Randomized clinical trial involving 44 subjects.
- Two groups: transconjunctival blepharoplasty with immediate or delayed CO2 laser resurfacing.
- Standardized photography and masked observer grading for outcome assessment.
Main Results:
- Transconjunctival blepharoplasty alone improved bulging (92%) but worsened wrinkles (46%).
- Combined blepharoplasty and CO2 laser resurfacing significantly improved wrinkles (P < 0.0005).
- Timing of laser resurfacing did not significantly affect outcomes; no lower lid retraction occurred.
Conclusions:
- Transconjunctival blepharoplasty with adjunctive CO2 laser resurfacing is an effective treatment for lower lid aging.
- This combination addresses fat pads and wrinkles without scarring or significant risk of retraction.
- It offers an excellent alternative to transcutaneous approaches for lower lid rejuvenation.

