Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Airway receptors.

J Widdicombe1

  • 1Human Physiology and Aerospace Medicine, GKT School of Biomedical Sciences, Shepherd's House, Guy's Campus, London Bridge, SE1 9RT, London, UK. johnwiddicombe@aol.com

Respiration Physiology
|March 10, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heart rate variability in hypertension caused by sleep disordered breathing and its modification by CPAP.

Bratislavske lekarske listy·2011
Same author

Workshop: tuning the 'cough center'.

Pulmonary pharmacology & therapeutics·2011
Same author

Semantics or pedantry?

The European respiratory journal·2010
Same author

The online Cough Clinic.

The European respiratory journal·2010
Same author

Distinct generators for aspiration and expiration reflexes: localization, mechanisms and effects.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2010
Same author

The expiration reflex from the trachea and bronchi.

The European respiratory journal·2007
Same journal

Braking of expiratory airflow in obese pigs during wakefulness and sleep.

Respiration physiology·2002
Same journal

Arousal response to hypoxia in newborn mice.

Respiration physiology·2002
Same journal

The oxygen gain of diving insects.

Respiration physiology·2002
Same journal

The role of endothelin-1 in strain-related susceptibility to develop hypoxic pulmonary hypertension in rats.

Respiration physiology·2002
Same journal

Active glottal closure during anoxic gasping in lambs.

Respiration physiology·2002
Same journal

Avian intrapulmonary chemoreceptor discharge rate is increased by anion exchange blocker 'DIDS'.

Respiration physiology·2002
See all related articles

Airway sensory receptors, including those in the larynx and trachea, are numerous but poorly correlated with specific afferent activities. Further research is needed to map these airway sensory structures and their reflex actions.

Area of Science:

  • Respiratory physiology
  • Neuroscience
  • Anatomy

Background:

  • The airways contain various afferent receptors, including pressure, cold, irritant, and C-fibre receptors in the larynx, and slowly and rapidly adapting stretch receptors (SARs and RARs), C-fibre receptors, and neuroepithelial bodies (NEBs) in the trachea and bronchi.
  • While histological identification of sensory structures is advanced, their correlation with specific afferent activities and reflex responses remains poor.

Purpose of the Study:

  • To review the current understanding of airway afferent receptors and their associated sensory structures.
  • To highlight the discrepancies between identified sensory structures and their physiological functions in the larynx, trachea, and bronchi.

Main Methods:

  • Review of existing literature on airway sensory receptors.

Related Experiment Videos

  • Analysis of histological and physiological data correlating sensory structures with afferent discharges and reflex responses.

    • Main Results:

    • In the larynx, four or more sensory structures lack definitive identification with afferent discharges and reflex responses.
    • In the trachea and bronchi, only SARs are clearly identified morphologically and physiologically.
    • Reflexes and afferent discharges from RARs and C-fibre receptors are understood, with some sensory terminals in the epithelium, but receptor complexes are not fully mapped.
    • Nerves in NEBs are identified, but their local and central reflex actions are not elucidated.

    Conclusions:

    • There is a significant gap in definitively linking identified airway sensory structures to their specific physiological roles and reflex actions.
    • Further research is required to map receptor complexes and elucidate the reflex actions of NEB nerves for a comprehensive understanding of airway sensory innervation.