Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thermal hysteresis proteins.

J Barrett1

  • 1Institute of Biological Sciences, University of Wales, Aberystwyth, Penglais, Ceredigion SY23 3DA, Aberystwyth, UK. jzb@aber.ac.uk

The International Journal of Biochemistry & Cell Biology
|March 10, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mindfulness moderates the relationship between emotional eating and body mass index in a sample of people with cystic fibrosis.

Eating and weight disorders : EWD·2020
Same author

Correction to: The contribution of iron deficiency to the risk of peripartum transfusion: a retrospective case control study.

BMC pregnancy and childbirth·2020
Same author

The contribution of iron deficiency to the risk of peripartum transfusion: a retrospective case control study.

BMC pregnancy and childbirth·2020
Same author

Improved Upper Limit on the Neutrino Mass from a Direct Kinematic Method by KATRIN.

Physical review letters·2019
Same author

Mid-trimester cervical consistency index measurement and prediction of preterm birth before 34 and 37 weeks in twin pregnancy.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2019
Same author

Utility of ultrasound assessment in management of pregnancies with preterm prelabor rupture of membranes.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2019
Same journal

Corrigendum to "Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels" [Int. J. Biochem. Cell Biol. 42 (2010) 1840-1846].

The international journal of biochemistry & cell biology·2026
Same journal

Whole-brain spatial metabolomics reveals metabolic gradient shifts in a murine glioma model following boron neutron capture therapy (130 characters).

The international journal of biochemistry & cell biology·2026
Same journal

LCN2 modulates Th17/Treg balance in vitro and is associated with an adaptive response to intestinal ischemia-reperfusion injury under Hmox1-deficient conditions.

The international journal of biochemistry & cell biology·2026
Same journal

Chloroquine modulates the redox-sensitive signalling via inhibiting the AMPK-ULK1 under LPS induced state in murine splenic macrophages.

The international journal of biochemistry & cell biology·2026
Same journal

The vicious cycle of hyperglycemia and oxidative stress: Novel mechanistic insights into a pathogenic alliance.

The international journal of biochemistry & cell biology·2026
Same journal

Fibroblast growth factors (FGF) in the pathogenesis and treatment of inflammatory bowel diseases (IBD): An overview.

The international journal of biochemistry & cell biology·2026
See all related articles

Thermal hysteresis proteins (THPs) are diverse molecules that prevent freezing by binding to ice crystals. These remarkable antifreeze proteins showcase convergent evolution across many species.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Evolutionary Biology

Background:

  • Extreme environments drive unique biochemical adaptations.
  • Thermal hysteresis proteins (THPs) are found across diverse life forms (vertebrates, invertebrates, plants, bacteria, fungi).
  • THPs non-colligatively depress the freezing point of water by binding to ice crystal surfaces.

Purpose of the Study:

  • To explore the diverse nature and evolutionary significance of thermal hysteresis proteins.
  • To understand the mechanisms behind THP ice-binding affinity and specificity.
  • To highlight the potential applications of THPs in cryopreservation and cold tolerance.

Main Methods:

  • Literature review of existing studies on THPs.
  • Analysis of protein structures and sequences.

Related Experiment Videos

  • Examination of experimental data on THP function and applications.

    • Main Results:

    • THPs exhibit diverse tertiary structures and lack conserved sequence motifs.
    • Different THPs interact with distinct ice crystal faces.
    • No single universal mechanism explains THP ice-binding.
    • THPs have demonstrated utility in cryopreservation and enhancing cold tolerance.

    Conclusions:

    • THPs are a prime example of parallel and convergent evolution.
    • The diverse structures and binding mechanisms of THPs reflect adaptation to antifreeze roles.
    • THPs hold significant potential for biotechnological applications in cold adaptation.