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Updated: Aug 13, 2026

In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
[Neurological manifestation of infectious endocarditis: 14 cases]
Abstract:
Fourteen cases of infective endocarditis revealed by neurological manifestations are reported: 8 strokes (one transient ischemic attack, one regressing and 6 completed strokes), 2 intracranial hematomas (one due to ruptured mycotic aneurysm), 2 toxic encephalopathies, one grand mal seizure, one suppurative meningitis. Most of them were native valve endocarditis, and streptococcus was the most frequently responsible bacteria. The outcome was characterized by a high mortality (6 cases) and morbidity (4 cases). This emphasizes the usefulness of preventing antibiotherapy in patients with known predisposing factors and the necessity for these patients to be admitted in neurological intensive care units.
Insights
Infective endocarditis frequently presents with serious neurological issues like strokes and brain bleeds. Prompt diagnosis and neurological intensive care are crucial for managing this severe heart infection.
Area of Science:
- Neurology
- Cardiology
- Infectious Diseases
Context:
- Infective endocarditis (IE) is a serious infection affecting heart valves.
- Neurological complications are common but often overlooked presenting signs of IE.
- This study focuses on IE cases initially presenting with neurological symptoms.
Purpose:
- To report and analyze cases of infective endocarditis primarily identified through neurological manifestations.
- To highlight the spectrum of neurological presentations associated with IE.
- To underscore the importance of considering IE in patients with unexplained neurological events.
Summary:
- Fourteen cases of infective endocarditis (IE) were identified through neurological symptoms.
- Presentations included strokes, intracranial hematomas, toxic encephalopathies, seizures, and meningitis.
- Native valve endocarditis caused by Streptococcus was most common.
- High mortality (6 cases) and morbidity (4 cases) were observed.
Impact:
- Highlights the critical role of neurological assessment in diagnosing IE.
- Emphasizes the need for preventative antibiotherapy in at-risk individuals.
- Stresses the importance of admitting patients with IE-related neurological complications to neurological intensive care units.
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Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Myocarditis II: Clinical Features and Diagnostic Tests
Encephalitis l: Introduction