Lead-induced hypertension. III. Increased hydroxyl radical production

Y Ding1, H C Gonick, N D Vaziri

  • 1Division of Nephrology and Hypertension, University of California, Irvine, USA.

Summary

This study suggests that lead-induced hypertension may involve reactive oxygen species, specifically hydroxyl radical or peroxynitrite. Dimethylthiourea, a scavenger, normalized blood pressure and oxidative stress markers in lead-treated rats.

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