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Related Experiment Videos

Monilial esophagitis.

N S Mann, V K Caplash

    Southern Medical Journal
    |April 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    A diabetic patient developed monilial esophagitis during gentamicin treatment for Escherichia coli septicemia. Prompt diagnosis via esophagoscopy and biopsy led to successful treatment with oral nystatin.

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    Area of Science:

    • Medical Mycology
    • Gastroenterology
    • Infectious Diseases

    Background:

    • Diabetes mellitus is a common comorbidity associated with an increased risk of opportunistic infections.
    • Escherichia coli septicemia is a serious bacterial infection requiring prompt antibiotic treatment.
    • Gentamicin is an aminoglycoside antibiotic frequently used for Gram-negative bacterial infections.

    Observation:

    • A case of monilial esophagitis (Candida esophagitis) was observed in a patient with diabetes mellitus.
    • The patient was undergoing treatment with gentamicin for Escherichia coli septicemia.
    • Initial diagnostic imaging, including an esophagogram, did not reveal abnormalities.

    Findings:

    • Fiberoptic esophagoscopy and subsequent biopsy confirmed the diagnosis of monilial esophagitis.

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  • The patient demonstrated a positive clinical response to oral nystatin therapy.
  • Review of existing literature on esophageal candidiasis was conducted.

    • Implications:

    • This case highlights the potential for opportunistic fungal infections like monilial esophagitis in immunocompromised patients, such as those with diabetes.
    • The findings underscore the importance of considering fungal superinfections in patients receiving broad-spectrum antibiotics.
    • Early diagnosis and appropriate antifungal treatment are crucial for managing monilial esophagitis effectively.