[Detection of silent ischemia symptoms in patients with carbohydrate metabolism disorders]

Early detection of silent ischaemia plays an important role in prevention of sudden cardiac death. Glucose metabolism disturbances are important risk factor of ischaemic heart disease. More frequent occurrence of silent ischaemia in patients with diabetes mellitus has been reported in several studies. We studied 24-hour Holter ECG monitoring of 335 patients with stable angina pectoris. Patients were divided in two groups. The first group consisted of 158 patients with glucose metabolism disturbances, the second-controlled group consisted of 177 patients without these disturbances. The aim of this study was to analyse the frequency of occurrence of silent ischaemia according to the grade of glucose metabolism disturbances. We only found that silent ischaemia is more frequent in patients with higher grade glucose metabolism disturbances. Additionally, we found that more frequent occurrence of silent ischaemia may depend on coexisting hypertension and hypertriglyceridemia. The comparison of Holter ECG monitoring and exercise test in detection of silent ischaemia has shown that both methods are useful in the detection of silent ischaemia.