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Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
[Pathomorphological aspects of the inflammatory process in soft tissues during the ozone application in the
Abstract:
In 35 white rats of Wistar line abscess of soft tissues was modelled. In animals of principle group influence of ozone-oxygenous gaseous mixture with concentration of ozone 0.1 mg/m3 times daily during 10 min were applied. While applicating ozone were noted reduction of exudative reaction and more rapid change of inflammatory phase, more early formation and maturation capsule around necrotic zone, than in control group, that promoted effective delineation of damage focus and enhancement of the inflammatory and dystrophic changes severity in tissues surrounding abscess.
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