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Thoracic computed tomography in patients with suspected malignant pleural effusions
Z C Traill1, R J Davies, F V Gleeson
1Department of Radiology, Churchill Hospital, Headington, Oxford, UK.
Clinical Radiology
|March 15, 2001
Summary
Contrast-enhanced computed tomography (CT) reliably identifies malignant pleural effusions. This imaging technique accurately detects cancerous pleural thickening, aiding diagnosis in patients with suspected malignancy.
Area of Science:
- Radiology
- Oncology
- Pulmonology
Background:
- Malignant pleural effusions are a common oncological complication.
- Accurate diagnosis is crucial for appropriate patient management and treatment.
Purpose of the Study:
- To prospectively evaluate the diagnostic role of contrast-enhanced computed tomography (CT) in patients with suspected malignant pleural effusions.
Main Methods:
- Forty patients with suspected malignant pleural effusion underwent contrast-enhanced thoracic CT.
- Pleural surfaces were assessed for malignancy using established CT criteria.
- Diagnosis was confirmed by histopathology, cytology, autopsy, or clinical follow-up.
Main Results:
- Malignant pleural effusions were present in 32 patients and benign in eight.
- Contrast-enhanced CT correctly identified malignancy in 84% of malignant effusions (sensitivity) and 100% of benign cases (specificity).
- Overall, CT correctly indicated malignancy in 87% of patients.
Conclusions:
- Contrast-enhanced CT is a valuable tool for diagnosing malignant pleural effusions.
- Established CT criteria for malignant pleural thickening, including nodularity, irregularity, and thickness >1 cm, are reliable in the presence of effusion.