Are desmosomes more than tethers for intermediate filaments?

K J Green1, C A Gaudry

  • 1Departments of Pathology and Dermatology and the Robert H. Lurie Cancer Center, Northwestern University Medical School, Chicago, Illinois 60611, USA. kgreen@nwu.edu

Summary

Desmosomes are cell junctions providing mechanical strength. They also act as sensors, responding to cues by changing their structure and signaling functions.

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