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12:48
The Multifaceted Benefits of Protein Co-expression in Escherichia coli
Published on: February 5, 2015
Escherichia coli DnaA protein--phospholipid interactions: in vitro and in vivo
1Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20007, USA. crooke@bc.georgetown.edu
Biochimie
|March 20, 2001
Abstract:
DNA replication in Escherichia coli is controlled at the initiation stage, possibly by regulation of the essential activity of DnaA protein. The cellular membrane has long been hypothesized to be involved in chromosomal replication. Accumulating evidence, both in vitro and in vivo, that supports the importance of membrane phospholipids influencing the initiation activity of DnaA is reviewed.
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